Naftopidil dihydrochloride
Naftopidil dihydrochloride is a dual antagonist of 5-HT1A and α1-adrenergic receptors, exhibiting IC50 values of 0.1 μM and 0.2 μM, respectively. This compound is utilized in research to investigate receptor functions in urological and cardiovascular systems, with applications in both in vitro binding assays and in vivo pharmacological studies.
Product Specifications
CAS Number
57149-08-3
Product Name Alternative
Canine, BM15275, BM-15275, BM 15275, AdrenergicReceptor, Adrenergic Receptor, 5-HT1A, 5HT Receptor, 5HTReceptor, KT 611, KT611, KT-611 2HCl, Naftopidil, Naftopidil DiHCl, hyperplasia, pressure, prostatic, α1-adrenergic receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.76% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:2 mg/mL (4.3 mM) ; DMSO:39 mg/mL (83.8 mM)
Smiles
Cl.Cl.COC1=CC=CC=C1N1CCN (CC (O) COC2=C3C=CC=CC3=CC=C2) CC1
Molecular Formula
C24H28N2O3·2HCl
Molecular Weight
465.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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