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Naratriptan hydrochloride

Naratriptan Hydrochloride is a selective serotonin 5-HT1B/1D receptor agonist used as an anti-migraine agent. Its mechanism involves cranial vasoconstriction and inhibition of pro-inflammatory neuropeptide release from trigeminal nerves, which has been validated in both in vitro receptor binding assays and in vivo models of migraine.

Product Specifications

CAS Number

143388-64-1

Product Name Alternative

Serotonin Receptor, 5-HT Receptor, 5-HT1, Amerge, 5HTReceptor, 5-hydroxytryptamine Receptor, 5HT Receptor, Inhibitor, GR-85548A, GR-85548A Hydrochloride, GR-85548A hydrochloride, inhibit, Naramig, Naratriptan, Naratriptan HCl, Naratriptan Hydrochloride, Naratriptan hydrochloride

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.17% (May vary between batches)

Solubility

DMSO:65 mg/mL (174.76 mM) ; H2O:20 mg/mL (53.77 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cl.CNS (=O) (=O) CCc1ccc2[nH]cc (C3CCN (C) CC3) c2c1

Molecular Formula

C17H25N3O2S·HCl

Molecular Weight

371.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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