What is the catalog number for Desmethyl Erlotinib hydrochloride?

The catalog number for Desmethyl Erlotinib hydrochloride is orb1300610.

What sizes are available for Desmethyl Erlotinib hydrochloride?

Desmethyl Erlotinib hydrochloride is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Desmethyl Erlotinib hydrochloride come in?

Desmethyl Erlotinib hydrochloride is available in 8 different pack sizes.

Is Desmethyl Erlotinib hydrochloride in stock?

Desmethyl Erlotinib hydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Desmethyl Erlotinib hydrochloride

Desmethyl Erlotinib hydrochloride (OSI-420) is the pharmacologically active metabolite of the EGFR inhibitor erlotinib. It potently inhibits EGFR tyrosine kinase activity and its autophosphorylation, with IC50 values of 2 nM and 20 nM, respectively. This compound is widely used in cancer research for in vitro mechanistic studies and in vivo models of EGFR-driven tumors.

Product Specifications

CAS Number

183320-51-6

Product Name Alternative

CP 473420, CP 373420, CP-373420, CP373420, CP-473420, CP473420, DesMethyl Erlotinib (CP-473420) HCl, Desmethyl Erlotinib hydrochloride, Desmethyl Erlotinib Hydrochloride, Desmethyl Erlotinib, Drug Metabolite, DrugMetabolite, inhibit, OSI420, OSI-420, OSI 420, EGFR, Inhibitor

Field of Research

Cardiovascular Research, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.03% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM) ; DMSO:77 mg/mL (185.15 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)