Raltitrexed
Raltitrexed (D1694) is a potent thymidylate synthase inhibitor with an IC50 of 9 nM, effectively suppressing L1210 leukemia cell growth in vitro. It is widely used in cancer research, including studies on colorectal carcinoma, both in cellular assays and in vivo models.
Product Specifications
CAS Number
112887-68-0
Product Name Alternative
ICI D 1694; ZD1694
Field of Research
Neuroscience
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
O=C1C=2C (=CC=C (CN (C) C=3SC (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) =CC3) C2) NC (C) =N1
Molecular Formula
C21H22N4O6S
Molecular Weight
458.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2S) -2-[[5-[Methyl-[ (2-methyl-4-oxo-3H-quinazolin-6-yl) methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid
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