Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Refametinib

Refametinib (RDEA119) is a potent and selective, ATP-noncompetitive inhibitor of MEK1 and MEK2 kinases, exhibiting IC50 values of 19 nM and 47 nM, respectively. It is widely used in cancer research, demonstrating antitumor activity in both in vitro cellular assays and in vivo models of various malignancies.

Product Specifications

CAS Number

923032-37-5

Product Name Alternative

Tumor, RDEA119, RDEA-119, Refametinib, RDEA 119, MAP2K, MAPKK, MEK, MEK1, MEK2, Inhibitor, inhibit, Mitogen-activated protein kinase kinase, orally, BAY 869766, BAY 86-97661, BAY869766, BAY-869766, allosteric

Field of Research

Signal Transduction

Purity

99.53% (May vary between batches)

Solubility

Ethanol:93 mg/mL (162.49 mM) ; DMSO:150 mg/mL (262.08 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

S (NC1=C (NC2=C (F) C=C (I) C=C2) C (F) =C (F) C=C1OC) (=O) (=O) C3 (C[C@@H] (CO) O) CC3

Molecular Formula

C19H20F3IN2O5S

Molecular Weight

572.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-PLA2G3 Mouse Monoclonal Antibody [Clone ID: OTI1F4]
M07886 100 µL

Anti-PLA2G3 Mouse Monoclonal Antibody [Clone ID: OTI1F4]

Sign In for Pricing
View Details
Anti-EGFL6 Antibody Picoband® (Dylight488 Conjugate)
A08756-Dylight488 100 µg

Anti-EGFL6 Antibody Picoband® (Dylight488 Conjugate)

Sign In for Pricing
View Details
ELISA Kit for Collagen Type I Alpha 2 (COL1a2)
TRV-0046908-01 24 Tests

ELISA Kit for Collagen Type I Alpha 2 (COL1a2)

Sign In for Pricing
View Details
ELISA Kit for Collagen Type I Alpha 2 (COL1a2)
TRV-0046908-02 48 Tests

ELISA Kit for Collagen Type I Alpha 2 (COL1a2)

Sign In for Pricing
View Details
ELISA Kit for Collagen Type I Alpha 2 (COL1a2)
TRV-0046908-03 96 Tests

ELISA Kit for Collagen Type I Alpha 2 (COL1a2)

Sign In for Pricing
View Details
ELISA Kit for Collagen Type I Alpha 2 (COL1a2)
TRV-0046908-04 5x 96 Tests

ELISA Kit for Collagen Type I Alpha 2 (COL1a2)

Sign In for Pricing
View Details