MZ 1
MZ-1 is a PROTAC-based small molecule that selectively degrades the BRD4 protein. It serves as a chemical probe for studying BRD4 function in oncology and transcriptional regulation research, with utility demonstrated in both cellular and in vivo models.
Product Specifications
CAS Number
1797406-69-9
Product Name Alternative
Degradation, Degrader, cells, BRD4, inhibit, Inhibitor, LS174t, MZ1, MZ-1, MZ 1, Epigenetic Reader Domain, EpigeneticReaderDomain, protein, PROTACs, selective
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.99 mM) ; DMSO:127.5 mg/mL (127.16 mM)
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (O) C4) C (C) (C) C) =O) =O) N=C2C7=CC=C (Cl) C=C7) =NN=C3C) SC1C
Molecular Formula
C49H60ClN9O8S2
Molecular Weight
1002.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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