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MZ 1

MZ-1 is a PROTAC-based small molecule that selectively degrades the BRD4 protein. It serves as a chemical probe for studying BRD4 function in oncology and transcriptional regulation research, with utility demonstrated in both cellular and in vivo models.

Product Specifications

CAS Number

1797406-69-9

Product Name Alternative

Degradation, Degrader, cells, BRD4, inhibit, Inhibitor, LS174t, MZ1, MZ-1, MZ 1, Epigenetic Reader Domain, EpigeneticReaderDomain, protein, PROTACs, selective

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Purity

99.31% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.99 mM) ; DMSO:127.5 mg/mL (127.16 mM)

Smiles

CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (O) C4) C (C) (C) C) =O) =O) N=C2C7=CC=C (Cl) C=C7) =NN=C3C) SC1C

Molecular Formula

C49H60ClN9O8S2

Molecular Weight

1002.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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