JQ-1 (carboxylic acid)
JQ-1 (carboxylic acid) is a potent, cell-permeable small molecule inhibitor of BRD4, exhibiting IC50 values of 77 nM and 33 nM for its first and second bromodomains, respectively. This compound is widely used in vitro and in vivo to study epigenetic regulation, cancer biology, and inflammation by blocking BET protein function.
Product Specifications
CAS Number
202592-23-2
Product Name Alternative
Polypeptide, remodeling, Epigenetic Reader Domain, EpigeneticReaderDomain, Inhibitor, inhibit, JQ 1, JQ 1 (carboxylic acid), JQ1, JQ-1, JQ1 (carboxylic acid), JQ-1 (carboxylic acid), JQ-1 carboxylic acid, bromodomain, carboxylic acid, chromatin, BRD4
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation
Purity
99.14% (May vary between batches)
Solubility
DMSO:125 mg/mL (311.81 mM) ; Ethanol:12.5 mg/mL (31.18 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.98 mM)
Smiles
CC=1C2=C (N3C ([C@H] (CC (O) =O) N=C2C4=CC=C (Cl) C=C4) =NN=C3C) SC1C
Molecular Formula
C19H17ClN4O2S
Molecular Weight
400.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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