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WNK-IN-11

WNK-IN-11 is a potent allosteric inhibitor of WNK1 kinase, exhibiting an IC50 of 4 nM. This small molecule is a valuable research tool for investigating WNK signaling pathways in hypertension and renal physiology through in vitro biochemical and cellular assays.

Product Specifications

CAS Number

2123489-30-3

Product Name Alternative

Inhibit, Inhibitor, Allosteric WNK Kinase Inhibitor, Serine proteases, Serine kinase, Ser/Thr Protease, Serine endopeptidases, threoninkinase, Threonine proteases, threonin kinase, Serinekinase, WNKIN11, WNK-IN-11, WNK1, WNK IN 11

Field of Research

Cell Biology, Metabolism Research, Protein Biochemistry

Purity

98.32% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.65 mM) ; H2O:Insoluble; DMSO:150 mg/mL (324.39 mM)

Smiles

CNc1nc (cs1) -c1cc (C (=O) N2CCN (Cc3ccc (Cl) cc3) CC2) c (Cl) cn1

Molecular Formula

C21H21Cl2N5OS

Molecular Weight

462.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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