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Darusentan

Darusentan (LU-135252) is a potent and selective endothelin receptor antagonist. It is used in research to study endothelin-mediated vasoconstriction in cardiovascular diseases, with applications in both in vitro assays and in vivo hypertension models.

Product Specifications

CAS Number

171714-84-4

Product Name Alternative

Darusentan, aortic, inhibit, muscle, Lu135252, Lu-135252, Lu 135252, Inhibitor, Endothelin Receptor, endothelin, Endothelin A receptor, EndothelinReceptor, ET-A, rat, receptor, RAVSMs, smooth, vascular

Field of Research

Pharmacology & Drug Discovery

Purity

97.26% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.75 mM) ; H2O:Insoluble; DMSO:125 mg/mL (304.56 mM)

Smiles

COc1cc (OC) nc (O[C@H] (C (O) =O) C (OC) (c2ccccc2) c2ccccc2) n1

Molecular Formula

C22H22N2O6

Molecular Weight

410.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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