GNE-6640
GNE-6640 is a potent and selective non-covalent inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 0.75 μM for the full-length enzyme. This compound is a valuable chemical probe for studying USP7's role in oncology and p53 pathway regulation in both cellular and biochemical assays.
Product Specifications
CAS Number
2009273-67-8
Product Name Alternative
USP7, DUBs, Deubiquitinase, inhibit, Inhibitor, GNE6640, GNE-6640, GNE 6640
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.64% (May vary between batches)
Solubility
DMSO:5 mg/mL (15.13 mM)
Smiles
CCc1c (cnc (N) c1-c1ccc (O) cc1) -c1ccc2[nH]ncc2c1
Molecular Formula
C20H18N4O
Molecular Weight
330.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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