XL 999
Tyrosine kinase-IN-1 is a potent multi-target inhibitor, demonstrating low nanomolar IC50 values against KDR (4 nM), Flt-1 (20 nM), FGFR1 (4 nM), and PDGFRα (2 nM) . This compound is a valuable research tool for studying angiogenesis and tumor cell proliferation in both cellular and animal models of cancer.
Product Specifications
CAS Number
705946-27-6
Product Name Alternative
Inhibitor, Fibroblast growth factor receptor, FGFR, FGFR1, FLT1, KDR, inhibit, Platelet-derived growth factor receptor, Tyrosine kinaseIN1, Tyrosine kinase-IN-1, Tyrosine kinase IN 1, Vascular endothelial growth factor receptor, VEGFR, PDGFR, PDGFRα
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.24% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.61 mM) ; DMSO:62.5 mg/mL (140.28 mM)
Smiles
CCN1CCC (CC1) Nc1ccc2NC (=O) \C (=C (/c3ncc (C) [nH]3) c3cccc (F) c3) c2c1
Molecular Formula
C26H28FN5O
Molecular Weight
445.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog