PQR620
PQR620 is a brain-penetrant small molecule that potently and selectively inhibits both mTORC1 and mTORC2 complexes. This inhibitor is a valuable research tool for studying mTOR signaling in neurological disorders and cancer, applicable in both in vitro biochemical assays and in vivo preclinical models.
Product Specifications
CAS Number
1927857-56-4
Product Name Alternative
Inhibit, mTORC1, mTORC2, mTOR, Inhibitor, Mammalian target of Rapamycin, PQR 620, PQR620, PQR-620
Field of Research
Signal Transduction
Purity
97.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.24 mM) ; DMSO:6.4 mg/mL (14.37 mM)
Smiles
[H][C@]12CC[C@] ([H]) (COC1) N2c1nc (nc (n1) -c1cnc (N) cc1C (F) F) N1[C@@]2 ([H]) CC[C@]1 ([H]) COC2
Molecular Formula
C21H25F2N7O2
Molecular Weight
445.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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