ELQ-300
ELQ-300 is a bioavailable antimalarial compound that selectively inhibits the cytochrome bc1 complex at its quinone reduction (Qi) site. It demonstrates potent efficacy in both in vitro assays against Plasmodium parasites and in vivo murine models of malaria, supporting its role as a promising chemotherapeutic candidate.
Product Specifications
CAS Number
1354745-52-0
Product Name Alternative
Recrudescence, ELQ 300, ELQ300, ELQ-300, Inhibitor, inhibit, infection, mice, Parasite, oral, antimalarial, acute
Field of Research
Infectious Disease & Virology
Purity
97.28% (May vary between batches)
Solubility
DMSO:15.62 mg/mL (32.83 mM)
Smiles
COc1cc2[nH]c (C) c (-c3ccc (Oc4ccc (OC (F) (F) F) cc4) cc3) c (=O) c2cc1Cl
Molecular Formula
C24H17ClF3NO4
Molecular Weight
475.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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