BI-4464
BI-4464 is a potent and selective ATP-competitive inhibitor of PTK2/FAK, demonstrating an IC50 of 17 nM. This small molecule serves as a ligand for PROTAC development and is utilized in cancer research to study focal adhesion signaling in both cellular and animal models.
Product Specifications
CAS Number
1227948-02-8
Product Name Alternative
BI 4464, BI4464, BI-4464, Focal adhesion kinase, FAK, inhibit, Inhibitor, Ligands for Target Protein for PROTAC, LigandsforTargetProteinforPROTAC, Target Protein-binding Moiety, PTK2, PTK2 protein tyrosine kinase 2, PTK2/FAK
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.43% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (30.01 mM)
Smiles
O (C1=C2C (CCC2=O) =CC=C1) C=3C (C (F) (F) F) =CN=C (NC4=C (OC) C=C (C (NC5CCN (C) CC5) =O) C=C4) N3
Molecular Formula
C28H28F3N5O4
Molecular Weight
555.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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