DMX-5804
DMX-5804 is a highly potent and selective MAP4K4 inhibitor exhibiting an IC50 of 3 nM. This compound has been shown to promote cardiomyocyte survival in vitro and demonstrates cardioprotective effects by mitigating ischemia-reperfusion injury in murine models.
Product Specifications
CAS Number
2306178-56-1
Product Name Alternative
MAPK Kinase Kinase Kinase, MAP4K, MAP4K4, MAP4K6, Inhibitor, inhibit, MINK1, DMX 5084, DMX 5804, DMX5084, DMX-5084, DMX5804, DMX-5804
Field of Research
Signal Transduction
Purity
99.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.07 mM) ; DMSO:125 mg/mL (345.89 mM)
Smiles
COCCOc1ccc (cc1) -c1cn (-c2ccccc2) c2nc[nH]c (=O) c12
Molecular Formula
C21H19N3O3
Molecular Weight
361.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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