AK-7
AK-7 is a brain-permeable small molecule inhibitor of SIRT2 with an IC50 of 15.5 μM. It has been investigated in vitro for its potential to reduce neuronal cholesterol, supporting research in neurodegenerative disease models such as Parkinson's and Huntington's disease.
Product Specifications
CAS Number
420831-40-9
Product Name Alternative
AK 7, AK7, AK-7, Inhibitor, inhibit, SIRT2, Sirtuin
Field of Research
Epigenetics & Chromatin, Neuroscience
Purity
>98%
Bioactivity
SIRT2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 8 mg/ml with warming) .
Smiles
Brc1cccc (NC (=O) c2cccc (c2) S (=O) (=O) N2CCCCCC2) c1
Molecular Formula
C19H21BrN2O3S
Molecular Weight
437.36
Storage Conditions
RT
Notes
For research use only.
Other Product Names
3- (1-Azepanylsulfonyl) -N- (3-bromophenyl) benzamide
Available Sizes
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