GSK3179106
GSK3179106 is a potent and selective small-molecule inhibitor of the RET kinase, demonstrating an IC50 of 0.4 nM. It is a valuable research tool for investigating RET-driven pathologies, such as certain cancers, in both cellular and animal models.
Product Specifications
CAS Number
1627856-64-7
Product Name Alternative
CRET, bowel, orally, inhibit, irritable, GSK 3179106, GSK3179106, GSK-3179106, hypersensitivity, IBS, Inhibitor, visceral, RET, syndrome, stress-induced, post-inflammatory
Field of Research
Cell Biology, Signal Transduction
Purity
99.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.56 mM) ; DMSO:100 mg/mL (213.94 mM) ; H2O:< 1 mg/mL (insoluble)
Smiles
CCOc1cc (=O) [nH]cc1-c1ccc (CC (=O) Nc2cc (on2) C (C) (C) C (F) (F) F) c (F) c1
Molecular Formula
C22H21F4N3O4
Molecular Weight
467.41
Storage Conditions
-20°C
Notes
For research use only.
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