SB-649868
SB-649868 (GSK649868) is a potent, selective, and orally bioavailable dual orexin receptor antagonist, exhibiting high affinity for both OX1 and OX2 receptors. It is a valuable research tool for investigating sleep-wake regulation, stress responses, and addiction pathways in both in vitro and in vivo models.
Product Specifications
CAS Number
380899-24-1
Product Name Alternative
OXReceptor, SB649868, SB-649868, SB 649868, inhibit, Inhibitor, OX Receptor, OX1, OX2, Orexin Receptor (OX Receptor), GSK 649868, GSK649868, GSK-649868, HCRT Receptor, Hypocretin Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.38 mM) ; DMSO:100 mg/mL (209.4 mM)
Smiles
Cc1nc (C (=O) N2CCCC[C@H]2CNC (=O) c2cccc3occc23) c (s1) -c1ccc (F) cc1
Molecular Formula
C26H24FN3O3S
Molecular Weight
477.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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