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JNJ16259685

JNJ16259685 is a potent and selective mGluR1 antagonist, demonstrating concentration-dependent inhibition of synaptic mGluR1 activation with an IC50 of 19 nM. This compound is a valuable research tool for investigating the role of mGluR1 in neurological disorders, including pain, ataxia, and addiction, in both in vitro and in vivo models.

Product Specifications

CAS Number

409345-29-5

Product Name Alternative

.TN.T 16259685, .TN.T16259685, .TN.T-16259685, inhibit, JNJ 16259685, JNJ16259685, JNJ-16259685, Inhibitor, Metabotropic glutamate receptors, mGluR, mGluR1

Field of Research

Neuroscience

Purity

98.31% (May vary between batches)

Solubility

DMSO:100 mg/mL (307.31 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.29 mM)

Smiles

CO[C@H]1CC[C@H] (CC1) C (=O) c1ccc2nc3OCCCc3cc2c1

Molecular Formula

C20H23NO3

Molecular Weight

325.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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