LOC14
LOC14 is the most potent small-molecule inhibitor of protein disulfide isomerase (PDI) currently reported, exhibiting an EC50 of 500 nM. This compound is a valuable research tool for investigating PDI's role in thrombus formation, cancer cell survival, and neurodegenerative diseases in both cellular and animal models.
Product Specifications
CAS Number
877963-94-5
Product Name Alternative
Inhibitor, inhibit, LOC 14, LOC14, LOC-14, PDI
Purity
98.22% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.3 mM) ; DMSO:50 mg/mL (157.52 mM)
Smiles
O=C (C1CC1) N1CCN (Cn2sc3ccccc3c2=O) CC1
Molecular Formula
C16H19N3O2S
Molecular Weight
317.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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