IDF-11774
IDF-11774 is a potent small molecule inhibitor of HIF-1, demonstrating an IC50 of 3.65 μM in reducing HIF-1α HRE-driven luciferase activity. This compound is a valuable research tool for studying hypoxia signaling pathways in cancer and other diseases, with applications in both cellular and animal models.
Product Specifications
CAS Number
1429054-28-3
Product Name Alternative
Inhibit, Hypoxia-inducible factors, IDF 11774, IDF11774, IDF-11774, Inhibitor, HIFs, HIFProlylHydroxylase, HIF-PH, HIF-1α, HIF, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
DMSO:60 mg/mL (162.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.71 mM)
Smiles
CN1CCN (CC1) C (=O) COc1ccc (cc1) C12CC3CC (CC (C3) C1) C2
Molecular Formula
C23H32N2O2
Molecular Weight
368.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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