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IDF-11774

IDF-11774 is a potent small molecule inhibitor of HIF-1, demonstrating an IC50 of 3.65 μM in reducing HIF-1α HRE-driven luciferase activity. This compound is a valuable research tool for studying hypoxia signaling pathways in cancer and other diseases, with applications in both cellular and animal models.

Product Specifications

CAS Number

1429054-28-3

Product Name Alternative

Inhibit, Hypoxia-inducible factors, IDF 11774, IDF11774, IDF-11774, Inhibitor, HIFs, HIFProlylHydroxylase, HIF-PH, HIF-1α, HIF, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research

Purity

98.00% (May vary between batches)

Solubility

DMSO:60 mg/mL (162.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.71 mM)

Smiles

CN1CCN (CC1) C (=O) COc1ccc (cc1) C12CC3CC (CC (C3) C1) C2

Molecular Formula

C23H32N2O2

Molecular Weight

368.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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