GSK8612
GSK8612 is a potent and selective small molecule inhibitor of Tank-binding kinase 1 (TBK1), exhibiting a pIC50 of 6.8. This compound is a valuable research tool for studying TBK1's role in immunology, oncology, and autophagy in both cellular and animal models.
Product Specifications
CAS Number
2361659-62-1
Product Name Alternative
IKK, IkB/IKK, IkB, I kappa B kinase, GSK 8612, GSK-8612, GSK8612, IκB kinase, IκB, Inhibitor, inhibit, TBK1
Field of Research
Immunology & Inflammation, Neuroscience
Purity
>98%
Bioactivity
TBK1 inhibitor (highly selective)
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
Cc1nn (CC (F) (F) F) cc1Nc1ncc (Br) c (NCc2ccc (cc2) S (N) (=O) =O) n1
Molecular Formula
C17H17BrF3N7O2S
Molecular Weight
520.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-[[[5-Bromo-2-[[3-methyl-1- (2,2,2-trifluoroethyl) pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
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