AK-1
AK-1 is a SIRT2 inhibitor with an IC50 of 12.5 μM. It exhibits neuroprotective effects in Alzheimer's disease models by promoting tubulin acetylation and also induces cell cycle arrest in colon carcinoma cells in vitro.
Product Specifications
CAS Number
330461-64-8
Product Name Alternative
Inhibit, Inhibitor, AK1, AK-1, AK 1, SIRT2, Sirtuin
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (4.96 mM) ; DMSO:40 mg/mL (99.14 mM)
Smiles
[O-][N+] (=O) c1cccc (NC (=O) c2cccc (c2) S (=O) (=O) N2CCCCCC2) c1
Molecular Formula
C19H21N3O5S
Molecular Weight
403.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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