SIS17
SIS17 is a cell-active, potent, and selective small molecule inhibitor of HDAC11, exhibiting an IC50 of 0.83 μM. It specifically blocks the demyristoylation of substrates like SHMT2 and is a valuable chemical probe for epigenetic research in oncology and immunology, applicable in both cellular and biochemical assays.
Product Specifications
CAS Number
2374313-54-7
Product Name Alternative
Inhibit, Inhibitor, HDAC, HDAC11, Histone deacetylases, SIS 17, SIS17, SIS-17
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.91 mM) ; DMSO:125 mg/mL (340.97 mM)
Smiles
CCCCCCCCCCCCCCCCNNC (=O) c1cccs1
Molecular Formula
C21H38N2OS
Molecular Weight
366.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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