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SIS17

SIS17 is a cell-active, potent, and selective small molecule inhibitor of HDAC11, exhibiting an IC50 of 0.83 μM. It specifically blocks the demyristoylation of substrates like SHMT2 and is a valuable chemical probe for epigenetic research in oncology and immunology, applicable in both cellular and biochemical assays.

Product Specifications

CAS Number

2374313-54-7

Product Name Alternative

Inhibit, Inhibitor, HDAC, HDAC11, Histone deacetylases, SIS 17, SIS17, SIS-17

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.91 mM) ; DMSO:125 mg/mL (340.97 mM)

Smiles

CCCCCCCCCCCCCCCCNNC (=O) c1cccs1

Molecular Formula

C21H38N2OS

Molecular Weight

366.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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