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H3B-5942

H3B-5942 is a selective estrogen receptor covalent antagonist (SERCA) that irreversibly targets ERα. It is a research tool used in vitro and in vivo to study endocrine-resistant breast cancer models and investigate novel therapeutic strategies for ER-positive malignancies.

Product Specifications

CAS Number

2052128-15-9

Product Name Alternative

EstrogenReceptor, Estrogen Receptor/ERR, H3B 5942, H3B5942, H-3B-5942, H3B-5942, Estrogen Receptor, ERα, ERR, inhibit, Inhibitor, progestogenReceptor, progestogen Receptor

Field of Research

Metabolism Research

Purity

≥95% (May vary between batches)

Solubility

DMSO:50 mg/mL (101.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.04 mM)

Smiles

CC\C (=C (\c1ccc (OCCNC\C=C\C (=O) N (C) C) cc1) c1ccc2[nH]ncc2c1) c1ccccc1

Molecular Formula

C31H34N4O2

Molecular Weight

494.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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