NG25
NG25 is a potent and selective small molecule inhibitor targeting both TAK1 and MAP4K2, with respective IC50 values of 149 nM and 21.7 nM. This compound is a valuable research tool for investigating inflammatory and oncogenic signaling pathways in both cellular and animal models.
Product Specifications
CAS Number
1315355-93-1
Product Name Alternative
MAP4K, MAP4K2/TAK1, MAP3K, MAPK Kinase Kinase Kinase, MAP kinase kinase kinase, MEKK, MAPKKK, Inhibitor, NG 25, NG25, NG-25, inhibit
Field of Research
Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (31.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.72 mM)
Smiles
CCN1CCN (Cc2ccc (NC (=O) c3ccc (C) c (Oc4ccnc5[nH]ccc45) c3) cc2C (F) (F) F) CC1
Molecular Formula
C29H30F3N5O2
Molecular Weight
537.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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