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Senexin A

Senexin A is a potent and selective small molecule inhibitor of CDK8 (Kd = 0.83 μM) and CDK19 (Kd = 0.31 μM) . It is a valuable research tool for studying the Mediator complex in oncology and inflammation, with utility in both in vitro biochemical assays and cellular pathway analysis.

Product Specifications

CAS Number

1366002-50-7

Product Name Alternative

Inhibitor, inhibit, CDK, CDK8, Cyclin dependent kinase, Senexin A

Field of Research

Cell Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.58 mM) ; DMSO:100 mg/mL (364.54 mM)

Smiles

N#Cc1ccc2ncnc (NCCc3ccccc3) c2c1

Molecular Formula

C17H14N4

Molecular Weight

274.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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