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Almonertinib hydrochloride

Almonertinib hydrochloride (HS-10296 hydrochloride) is a selective EGFR inhibitor targeting both activating and T790M resistance mutations. It is widely used in preclinical in vitro and in vivo studies for non-small cell lung cancer (NSCLC) research, demonstrating efficacy in cellular assays and animal models.

Product Specifications

CAS Number

2134096-03-8

Product Name Alternative

Non-small, lung, mutations, inhibit, NSCLC, oral, EGFR, ErbB-1, Epidermal growth factor receptor, G719X, Inhibitor, HER1, HS10296, HS-10296, HS10296 Hydrochloride, HS-10296 hydrochloride, HS-10296 Hydrochloride, L858R, L861Q, HS 10296, HS 10296 Hydrochloride, del19, cell, cancer, antineoplastic, Almonertinib, Almonertinib hydrochloride, Almonertinib Hydrochloride

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.01% (May vary between batches)

Solubility

DMSO:83.33 mg/mL (148.25 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.87 mM)

Smiles

Cl.COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1cn (C2CC2) c2ccccc12

Molecular Formula

C30H36ClN7O2

Molecular Weight

562.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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