Ethyl 3,4-dihydroxybenzoate
Ethyl 3,4-dihydroxybenzoate (EDHB) is a cell-permeable prolyl hydroxylase inhibitor used in hypoxia research. It has demonstrated efficacy in attenuating acute hypobaric hypoxia-induced vascular leakage in the brain in vivo, making it a valuable tool for studying HIF stabilization and related pathways.
Product Specifications
CAS Number
3943-89-3
Product Name Alternative
Prolyl hydroxylase, prolyl-hydroxylase, ROS, ReactiveOxygenSpecies, Reactive Oxygen Species, Hypoxia-inducible factors, Inhibitor, HIF, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIF-PH, HIFProlylHydroxylase, HIFs, Ethyl protocatechuate, Ethyl 3,4 dihydroxybenzoate, Ethyl 3,4dihydroxybenzoate, Ethyl 3,4-dihydroxybenzoate, inhibit, NOSynthase, NOS, mitochondrial, NO Synthase, Nitric oxide synthases, collagen, antioxidant, Apoptosis, Autophagy
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (123.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.98 mM)
Smiles
CCOC (=O) C1=CC (O) =C (O) C=C1
Molecular Formula
C9H10O4
Molecular Weight
182.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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