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BMS-1166

BMS-1166 is a small molecule inhibitor that potently disrupts the PD-1/PD-L1 immune checkpoint pathway. It is widely used in immuno-oncology research to study T-cell reactivation and has demonstrated activity in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

1818314-88-3

Product Name Alternative

Cell, checkpoint, dimerization, activation, BMS 1166, BMS1166, BMS-1166, interaction, PD1, PD-1, PD1/PDL1, PD-1/PD-L1, immune, inhibit, Inhibitor, PDL1, PD-L1

Field of Research

Cell Biology, Immunology & Inflammation

Purity

99.14% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.24 mM) ; DMSO:125 mg/mL (194.97 mM)

Smiles

Cc1c (COc2cc (OCc3cccc (c3) C#N) c (CN3C[C@H] (O) C[C@@H]3C (O) =O) cc2Cl) cccc1-c1ccc2OCCOc2c1

Molecular Formula

C36H33ClN2O7

Molecular Weight

641.11

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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