BMS-1166
BMS-1166 is a small molecule inhibitor that potently disrupts the PD-1/PD-L1 immune checkpoint pathway. It is widely used in immuno-oncology research to study T-cell reactivation and has demonstrated activity in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
1818314-88-3
Product Name Alternative
Cell, checkpoint, dimerization, activation, BMS 1166, BMS1166, BMS-1166, interaction, PD1, PD-1, PD1/PDL1, PD-1/PD-L1, immune, inhibit, Inhibitor, PDL1, PD-L1
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.14% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.24 mM) ; DMSO:125 mg/mL (194.97 mM)
Smiles
Cc1c (COc2cc (OCc3cccc (c3) C#N) c (CN3C[C@H] (O) C[C@@H]3C (O) =O) cc2Cl) cccc1-c1ccc2OCCOc2c1
Molecular Formula
C36H33ClN2O7
Molecular Weight
641.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP48452_P050-Biotin 100 µL
C19orf47 Antibody - middle region : Biotin (ARP48452_P050-Biotin)
Sign In for Pricing
View Details 
FMA30112 100 Tests
Anti-Mouse CD304/NRP1/NRP2 Antibody (YW68.11.26), PE
Sign In for Pricing
View Details abx343496-01 50 µL
HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) Antibody (Biotin)
Sign In for Pricing
View Details abx343496-02 100 µL
HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) Antibody (Biotin)
Sign In for Pricing
View Details abx343496-03 200 µL
HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) Antibody (Biotin)
Sign In for Pricing
View Details abx343496-04 1 mL
HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) Antibody (Biotin)
Sign In for Pricing
View Details