BMS-1166
BMS-1166 is a small molecule inhibitor that potently disrupts the PD-1/PD-L1 immune checkpoint pathway. It is widely used in immuno-oncology research to study T-cell reactivation and has demonstrated activity in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
1818314-88-3
Product Name Alternative
Cell, checkpoint, dimerization, activation, BMS 1166, BMS1166, BMS-1166, interaction, PD1, PD-1, PD1/PDL1, PD-1/PD-L1, immune, inhibit, Inhibitor, PDL1, PD-L1
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.14% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.24 mM) ; DMSO:125 mg/mL (194.97 mM)
Smiles
Cc1c (COc2cc (OCc3cccc (c3) C#N) c (CN3C[C@H] (O) C[C@@H]3C (O) =O) cc2Cl) cccc1-c1ccc2OCCOc2c1
Molecular Formula
C36H33ClN2O7
Molecular Weight
641.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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