TRPM8 antagonist 2
TRPM8 antagonist 2 is a highly potent and selective inhibitor of the TRPM8 ion channel, exhibiting an IC50 of 0.2 nM. It is a valuable research tool for investigating neuropathic pain mechanisms in both in vitro cellular assays and in vivo animal models of cold allodynia.
Product Specifications
CAS Number
259674-19-6
Product Name Alternative
Inhibit, Inhibitor, Transient receptor potential channels, TRP Channel, TRPV Channel, TRPM8 antagonist 2, TRPM-8 antagonist 2, TRPChannel, TRPM8, TRPVChannel
Field of Research
Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.04 mM) ; DMSO:160 mg/mL (401.51 mM)
Smiles
COC (=O) [C@H] (Cc1c[nH]c2ccccc12) N (Cc1ccccc1) Cc1ccccc1
Molecular Formula
C26H26N2O2
Molecular Weight
398.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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