7-Epi 10-desacetyl paclitaxel
7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) is a potent microtubule-stabilizing agent, exhibiting an IC50 of 0.085 nM against HeLa cervical cancer cells in vitro. This taxane derivative is a valuable research tool for studying mechanisms of cytotoxicity and resistance in cancer biology, with applications in both cellular and biochemical assays.
Product Specifications
CAS Number
78454-17-8
Product Name Alternative
ADC Cytotoxin, ADCCytotoxin, 7-Epi 10-desacetyl paclitaxel, 7Epi 10desacetyl paclitaxel, 7-Epi-10-deacetyltaxol, 7 Epi 10 desacetyl paclitaxel, 10-Deacetyl-7-epipaclitaxel, Inhibitor, inhibit
Field of Research
Pharmacology & Drug Discovery; Cell Biology
Purity
98.05% (May vary between batches)
Solubility
DMSO:8.12 mg/mL (10 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.23 mM)
Smiles
[H][C@@]12C[C@@H] (O) [C@@]3 (C) C (=O) [C@H] (O) C4=C (C) [C@H] (C[C@@] (O) ([C@@H] (OC (=O) c5ccccc5) [C@]3 ([H]) [C@@]1 (CO2) OC (C) =O) C4 (C) C) OC (=O) [C@H] (O) [C@@H] (NC (=O) c1ccccc1) c1ccccc1
Molecular Formula
C45H49NO13
Molecular Weight
811.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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