GSK3326595
GSK3326595 (EPZ015938) is a potent and selective PRMT5 inhibitor with an IC50 of 6.2 nM. It is a valuable chemical probe for investigating the role of PRMT5-mediated methylation in oncology, hematology, and immunology research, demonstrating activity in both cellular and animal models.
Product Specifications
CAS Number
1616392-22-3
Product Name Alternative
EPZ015938
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
Selective PRMT5 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
CC (=O) N1CCC (CC1) Nc1cc (ncn1) C (=O) NC[C@@H] (O) CN1CCc2ccccc2C1
Molecular Formula
C24H32N6O3
Molecular Weight
452.56
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6-[ (1-Acetylpiperidine-4-yl) amino]-N-[ (2S) -3- (3,4-dihydro-1H-isoquinolin-2-yl) -2-hydroxypropyl]pyrimidine-4-carboxamide
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