Topotecan
Topotecan (NSC-609669) is a small molecule antineoplastic agent that functions as a Topoisomerase I inhibitor. It is widely used in oncology research, particularly for studying ovarian cancer, and is applied in both in vitro cell-based assays and in vivo xenograft models to investigate its mechanism and efficacy.
Product Specifications
CAS Number
123948-87-8
Product Name Alternative
Autophagy, inhibit, NSC 609669, orally active, NSC609669, NSC-609669, Inhibitor, Eukaryotic topoisomerase I, GSCs-U251, GSCs-U87, Topoisomerase, Topotecan, SKF 104864A, U251, U87
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
95.06% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.83 mM) ; DMSO:84 mg/mL (199.31 mM)
Smiles
CC[C@@]1 (O) C (=O) OCc2c1cc1-c3nc4ccc (O) c (CN (C) C) c4cc3Cn1c2=O
Molecular Formula
C23H23N3O5
Molecular Weight
421.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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