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MJN110

MJN110 is a potent and selective inhibitor of monoacylglycerol lipase (MAGL) with an IC50 of 9.1 nM. This compound demonstrates opioid-sparing effects in murine neuropathic pain models, supporting its use in research on endocannabinoid signaling, pain mechanisms, and potential analgesic development in both in vitro and in vivo studies.

Product Specifications

CAS Number

1438416-21-7

Product Name Alternative

Inhibit, MJN 110, MJN110, MJN-110, MAGL, Monoacylglycerol lipase, Inhibitor, Cravatt Reagent

Field of Research

Metabolism Research

Purity

98.00% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (59.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.33 mM)

Smiles

Clc1ccc (cc1) C (N1CCN (CC1) C (=O) ON1C (=O) CCC1=O) c1ccc (Cl) cc1

Molecular Formula

C22H21Cl2N3O4

Molecular Weight

462.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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