MJN110
MJN110 is a potent and selective inhibitor of monoacylglycerol lipase (MAGL) with an IC50 of 9.1 nM. This compound demonstrates opioid-sparing effects in murine neuropathic pain models, supporting its use in research on endocannabinoid signaling, pain mechanisms, and potential analgesic development in both in vitro and in vivo studies.
Product Specifications
CAS Number
1438416-21-7
Product Name Alternative
Inhibit, MJN 110, MJN110, MJN-110, MAGL, Monoacylglycerol lipase, Inhibitor, Cravatt Reagent
Field of Research
Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (59.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.33 mM)
Smiles
Clc1ccc (cc1) C (N1CCN (CC1) C (=O) ON1C (=O) CCC1=O) c1ccc (Cl) cc1
Molecular Formula
C22H21Cl2N3O4
Molecular Weight
462.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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