PKC-theta inhibitor hcl
This small molecule is a potent and selective inhibitor of protein kinase C theta (PKC-θ), exhibiting an IC50 of 12 nM. It is a valuable research tool for studying T-cell activation and has been utilized in both in vitro and in vivo models of autoimmune and inflammatory diseases.
Product Specifications
CAS Number
2253640-49-0
Product Name Alternative
PKCtheta inhibitor hcl, PKC-theta inhibitor hcl, PKC theta inhibitor hcl, PKCθ
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:55 mg/mL (112.04 mM)
Smiles
Cl.NCC1CCC (CNc2nc (NCc3ccccc3OC (F) (F) F) ncc2[N+] ([O-]) =O) CC1
Molecular Formula
C20H26ClF3N6O3
Molecular Weight
490.91
Storage Conditions
-20°C
Notes
For research use only.
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