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PKC-theta inhibitor hcl

This small molecule is a potent and selective inhibitor of protein kinase C theta (PKC-θ), exhibiting an IC50 of 12 nM. It is a valuable research tool for studying T-cell activation and has been utilized in both in vitro and in vivo models of autoimmune and inflammatory diseases.

Product Specifications

CAS Number

2253640-49-0

Product Name Alternative

PKCtheta inhibitor hcl, PKC-theta inhibitor hcl, PKC theta inhibitor hcl, PKCθ

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:55 mg/mL (112.04 mM)

Smiles

Cl.NCC1CCC (CNc2nc (NCc3ccccc3OC (F) (F) F) ncc2[N+] ([O-]) =O) CC1

Molecular Formula

C20H26ClF3N6O3

Molecular Weight

490.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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