JMS-17-2
JMS-17-2 is a highly potent and selective CX3CR1 antagonist with a sub-nanomolar IC50 of 0.32 nM. This small molecule inhibitor is a valuable research tool for investigating the role of the CX3CL1/CX3CR1 axis in neuroinflammation, atherosclerosis, and other disease models in both cellular and animal studies.
Product Specifications
CAS Number
1380392-05-1
Product Name Alternative
Inhibitor, GPR13, fractalkine receptor, JMS 17 2, JMS172, JMS-17-2, inhibit, CX3C chemokine receptor1, CX3CR1
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:11 mg/mL (26.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.76 mM)
Smiles
Clc1ccc (cc1) C1CCN (CCCn2c3ccccc3n3cccc3c2=O) CC1
Molecular Formula
C25H26ClN3O
Molecular Weight
419.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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