Benzamil
Benzamil is a potent and selective inhibitor of the epithelial sodium channel (ENaC), exhibiting an IC50 of 4 nM for sodium transport inhibition and a Kd of 5 nM for binding in bovine kidney models. This amiloride analog is widely used in research to investigate sodium homeostasis, airway surface liquid regulation, and hypertension mechanisms in both cellular and animal studies.
Product Specifications
CAS Number
2898-76-2
Product Name Alternative
ENaC, myogenic, Na+ Exchanger, Na+/Ca2+ Exchanger, Na+Exchanger, Ca2+Exchanger, Ca2+ Exchanger, Benzamil, Benzylamiloride, vasoconstriction, Sodium Channel, SodiumChannel, podocytes
Field of Research
Pharmacology & Drug Discovery
Purity
99.30% (May vary between batches)
Solubility
DMSO:3.2 mg/mL (10.01 mM)
Smiles
C (NC (NCC1=CC=CC=C1) =N) (=O) C=2C (N) =NC (N) =C (Cl) N2
Molecular Formula
C13H14ClN7O
Molecular Weight
319.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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