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AM-580

AM580 (CD336) is a potent and selective retinoic acid receptor alpha (RARα) agonist with an IC50 of 8 nM. It is widely used in research to study RARα-mediated signaling in cellular differentiation, proliferation, and apoptosis, with applications in both in vitro assays and in vivo models of development and disease.

Product Specifications

CAS Number

102121-60-8

Product Name Alternative

CD336; NSC 608001; Ro 40-6055

Field of Research

Cardiovascular Research, Cell Biology, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

Retinoid RARα agonist

Form

Powder

Solubility

Soluble in DMSO (35 mg/ml) ; or Ethanol (18 mg/ml)

Smiles

CC1 (C) CCC (C) (C) c2cc (ccc12) C (=O) Nc1ccc (cc1) C (O) =O

Molecular Formula

C22H25NO3

Molecular Weight

351.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

4-[ (5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) carboxamido]benzoic acid

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