3-Bromopyruvic acid
3-Bromopyruvic acid (3-BP) is a potent hexokinase II inhibitor with a Ki of 2.4 mM, disrupting glycolytic energy metabolism in tumor cells. It has demonstrated antitumor activity in vitro and in vivo and can act as a chemopotentiator for platinum-based chemotherapeutics in cancer research.
Product Specifications
CAS Number
1113-59-3
Product Name Alternative
3Bromopyruvic acid, 3-Bromopyruvic acid, 3 Bromopyruvic acid, analogue, Apoptosis, Autophagy, Bromopyruvic acid, cells, Inhibitor, hexokinase II, Hexokinase II Inhibitor II, 3-BP, Hexokinase, MCF-7, glycolysis, inhibit, pyruvate, stress
Field of Research
Cell Biology, Metabolism Research
Purity
95.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.98 mM) ; H2O:32 mg/mL (191.66 mM) ; DMSO:122.5 mg/mL (733.71 mM)
Smiles
OC (=O) C (=O) CBr
Molecular Formula
C3H3BrO3
Molecular Weight
166.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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