Imidafenacin
Imidafenacin (KRP-197/ONO-8025) is a highly potent and selective M3 muscarinic receptor antagonist with a Kb of 0.317 nM. It is widely used in research to investigate overactive bladder pathophysiology, employing both in vitro binding assays and in vivo animal models of bladder dysfunction.
Product Specifications
CAS Number
170105-16-5
Product Name Alternative
KRP 197, KRP197, KRP-197, inhibit, Muscarinic acetylcholine receptor, mAChR, ONO 8025, ONO8025, ONO-8025, Imidafenacin, Inhibitor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.05% (May vary between batches)
Solubility
DMSO:65 mg/mL (203.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.26 mM)
Smiles
Cc1nccn1CCC (C (N) =O) (c1ccccc1) c1ccccc1
Molecular Formula
C20H21N3O
Molecular Weight
319.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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