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Boceprevir

Boceprevir is a potent and selective oral inhibitor of the HCV NS3 protease, exhibiting a Ki of 14 nM in enzymatic assays and an EC90 of 350 nM in cellular replicon systems. It has been utilized in both in vitro and in vivo research to study hepatitis C virus replication and protease inhibitor mechanisms.

Product Specifications

CAS Number

394730-60-0

Product Name Alternative

SCH 503034

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

Antiviral; SARS-CoV-2 Mpro inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 15 mg/ml) ; or Ethanol (25 mg/ml)

Smiles

C (NC (CC1CCC1) C (C (N) =O) =O) (=O) [C@@H]2[C@@]3 ([C@@] (C3 (C) C) (CN2C ([C@@H] (NC (NC (C) (C) C) =O) C (C) (C) C) =O) [H]) [H]

Molecular Formula

C27H45N5O5

Molecular Weight

519.7

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(1R,2S,5S) -N-[3-amino-1- (cyclobutylmethyl) -2,3-dioxopropyl]-3-[ (2S) -2-[[[ (1,1-dimethylethyl) amino]carbonyl]amino]-3,3-3-azabicyclo[3.1.0]hexane-2-carboxamide

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