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Cinobufotalin

Cinobufotalin, a cardiac toxin from toad venom, exhibits anti-hepatocellular carcinoma (HCC) activity by inducing growth arrest and apoptosis via ceramide generation in vitro. It reverses multidrug resistance by downregulating P-gp and MRP-1, and enhances the maturation and function of dendritic cells from chronic hepatitis B patients, potentially boosting antiviral immunity.

Product Specifications

CAS Number

1108-68-5

Product Name Alternative

P-gp, Pgp, Akt, Cinobufotalin, ILReceptor, IL Receptor, Inhibitor, inhibit, MRP1, MRP-1

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.92% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM) ; DMSO:50 mg/mL (109.04 mM)

Smiles

CC (=O) O[C@H]1[C@H]2O[C@]22[C@@H]3CC[C@]4 (O) C[C@@H] (O) CC[C@]4 (C) [C@H]3CC[C@]2 (C) [C@H]1c1ccc (=O) oc1

Molecular Formula

C26H34O7

Molecular Weight

458.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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