Cinobufotalin
Cinobufotalin, a cardiac toxin from toad venom, exhibits anti-hepatocellular carcinoma (HCC) activity by inducing growth arrest and apoptosis via ceramide generation in vitro. It reverses multidrug resistance by downregulating P-gp and MRP-1, and enhances the maturation and function of dendritic cells from chronic hepatitis B patients, potentially boosting antiviral immunity.
Product Specifications
CAS Number
1108-68-5
Product Name Alternative
P-gp, Pgp, Akt, Cinobufotalin, ILReceptor, IL Receptor, Inhibitor, inhibit, MRP1, MRP-1
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.92% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM) ; DMSO:50 mg/mL (109.04 mM)
Smiles
CC (=O) O[C@H]1[C@H]2O[C@]22[C@@H]3CC[C@]4 (O) C[C@@H] (O) CC[C@]4 (C) [C@H]3CC[C@]2 (C) [C@H]1c1ccc (=O) oc1
Molecular Formula
C26H34O7
Molecular Weight
458.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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